Cargando…

Insulin-like Growth Factor 1 Signaling in Mammalian Hearing

Insulin-like growth factor 1 (IGF-1) is a peptide hormone belonging to the insulin family of proteins. Almost all of the biological effects of IGF-1 are mediated through binding to its high-affinity tyrosine kinase receptor (IGF1R), a transmembrane receptor belonging to the insulin receptor family....

Descripción completa

Detalles Bibliográficos
Autores principales:	García-Mato, Ángela, Cervantes, Blanca, Murillo-Cuesta, Silvia, Rodríguez-de la Rosa, Lourdes, Varela-Nieto, Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535591/ https://www.ncbi.nlm.nih.gov/pubmed/34680948 http://dx.doi.org/10.3390/genes12101553

Ejemplares similares

The Role of Insulin-Like Growth Factor-I in the Physiopathology of Hearing
por: Murillo-Cuesta, Silvia, et al.
Publicado: (2011)

The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss
por: Rodríguez-de la Rosa, Lourdes, et al.
Publicado: (2017)

A Comparative Study of Age-Related Hearing Loss in Wild Type and Insulin-Like Growth Factor I Deficient Mice
por: Riquelme, Raquel, et al.
Publicado: (2010)

IGF-1 Controls Metabolic Homeostasis and Survival in HEI-OC1 Auditory Cells through AKT and mTOR Signaling
por: García-Mato, Ángela, et al.
Publicado: (2023)

Therapeutic efficiency of the APAF‐1 antagonist LPT99 in a rat model of cisplatin‐induced hearing loss
por: Murillo‐Cuesta, Silvia, et al.
Publicado: (2021)

Transforming growth factor β1 inhibition protects from noise-induced hearing loss
por: Murillo-Cuesta, Silvia, et al.
Publicado: (2015)

Corrigendum: Transforming growth factor β1 inhibition protects from noise-induced hearing loss
por: Murillo-Cuesta, Silvia, et al.
Publicado: (2015)

Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges
por: Varela-Nieto, Isabel, et al.
Publicado: (2021)

Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss
por: Celaya, Adelaida M, et al.
Publicado: (2019)

Solid Lipid Nanoparticles Loaded with Glucocorticoids Protect Auditory Cells from Cisplatin-Induced Ototoxicity
por: Cervantes, Blanca, et al.
Publicado: (2019)

Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice
por: Martínez-Vega, Raquel, et al.
Publicado: (2016)

Autophagy resolves early retinal inflammation in Igf1-deficient mice
por: Arroba, Ana I., et al.
Publicado: (2016)

Corrigendum to: Swept-sine noise-induced damage as a hearing loss model for preclinical assays
por: Sanz, Lorena, et al.
Publicado: (2015)

Swept-sine noise-induced damage as a hearing loss model for preclinical assays
por: Sanz, Lorena, et al.
Publicado: (2015)

Biomarkers in Vestibular Schwannoma–Associated Hearing Loss
por: Lassaletta, Luis, et al.
Publicado: (2019)

Treatment with N- and C-Terminal Peptides of Parathyroid Hormone-Related Protein Partly Compensate the Skeletal Abnormalities in IGF-I Deficient Mice
por: Rodríguez-de la Rosa, Lourdes, et al.
Publicado: (2014)

Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea
por: Bermúdez-Muñoz, Jose M., et al.
Publicado: (2021)

IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss
por: Celaya, Adelaida M., et al.
Publicado: (2021)

Editorial: Aging, neurogenesis and neuroinflammation in hearing loss and protection
por: Magariños, Marta, et al.
Publicado: (2015)

Effects of Insulin-Like Growth Factor (IGF-1) in Patients with Sensorineural Hearing Loss
por: Dave, Varun Jitendra, et al.
Publicado: (2021)

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss
por: Partearroyo, Teresa, et al.
Publicado: (2017)

C-Raf deficiency leads to hearing loss and increased noise susceptibility
por: de Iriarte Rodríguez, Rocío, et al.
Publicado: (2015)

A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
por: Murillo-Cuesta, Silvia, et al.
Publicado: (2017)

Jejunal microvilli atrophy and reduced nutrient transport in rats with advanced liver cirrhosis: improvement by Insulin-like Growth Factor I
por: Castilla-Cortázar, Inma, et al.
Publicado: (2004)

Targeting Cholesterol Homeostasis to Fight Hearing Loss: A New Perspective
por: Malgrange, Brigitte, et al.
Publicado: (2015)

Insulin-Like Growth Factor-1 and Neuroinflammation
por: Labandeira-Garcia, Jose L., et al.
Publicado: (2017)

Insulin-Like Growth Factor-Binding Proteins of Teleost Fishes
por: Garcia de la Serrana, Daniel, et al.
Publicado: (2018)

Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury
por: Genis, Laura, et al.
Publicado: (2014)

Neuroglial Involvement in Abnormal Glutamate Transport in the Cochlear Nuclei of the Igf1(−/−) Mouse
por: Fuentes-Santamaría, Veronica, et al.
Publicado: (2019)

Insulin-like growth factor-1 deficiency and metabolic syndrome
por: Aguirre, G. A., et al.
Publicado: (2016)

RNA Microarray Analysis in Prenatal Mouse Cochlea Reveals Novel IGF-I Target Genes: Implication of MEF2 and FOXM1 Transcription Factors
por: Sanchez-Calderon, Hortensia, et al.
Publicado: (2010)

Role of Insulin-like Growth Factor, Insulin-like Growth Factor Receptors, and Insulin-like Growth Factor-binding Proteins in Ovarian Cancer
por: Amutha, Periyasamy, et al.
Publicado: (2017)

Insulin-like Growth Factor 1 in relation to future hearing impairment: findings from the English Longitudinal Study of Ageing
por: Lassale, Camille, et al.
Publicado: (2017)

Ultrasound Microbubbles Enhance the Efficacy of Insulin-Like Growth Factor-1 Therapy for the Treatment of Noise-Induced Hearing Loss
por: Lin, Yi-Chun, et al.
Publicado: (2021)

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
por: Espino Guarch, Meritxell, et al.
Publicado: (2018)

Insulin-like growth factors and insulin-like growth factor binding proteins in mammary gland function
por: Marshman, Emma, et al.
Publicado: (2002)

The Role of Insulin-Like Growth Factors and Insulin-Like Growth Factor–Binding Proteins in the Nervous System
por: Lewitt, Moira S, et al.
Publicado: (2019)

Divergent and convergent roles for insulin-like peptides in the worm, fly and mammalian nervous systems
por: Lau, Hiu E., et al.
Publicado: (2014)

The Insulin-Like Growth Factor System
por: Roith, Derek Le
Publicado: (2003)

Insulin-like growth factors and cancer.
por: Macaulay, V. M.
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_jjqeeibulsoc0rsaoaajbc8mgd