AMaLa: Analysis of Directed Evolution Experiments via Annealed Mutational Approximated Landscape

We present Annealed Mutational approximated Landscape (AMaLa), a new method to infer fitness landscapes from Directed Evolution experiments sequencing data. Such experiments typically start from a single wild-type sequence, which undergoes Darwinian in vitro evolution via multiple rounds of mutation...

Descripción completa

Detalles Bibliográficos
Autores principales: Sesta, Luca, Uguzzoni, Guido, Fernandez-de-Cossio-Diaz, Jorge, Pagnani, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535593/
https://www.ncbi.nlm.nih.gov/pubmed/34681569
http://dx.doi.org/10.3390/ijms222010908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535593/
https://www.ncbi.nlm.nih.gov/pubmed/34681569
http://dx.doi.org/10.3390/ijms222010908

Ejemplares similares