Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications

Epigenetics involves a series of mechanisms that entail histone and DNA covalent modifications and non-coding RNAs, and that collectively contribute to programing cell functions and differentiation. Epigenetic anomalies and DNA mutations are co-drivers of cellular dysfunctions, including carcinogene...

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Detalles Bibliográficos
Autores principales: Desaulniers, Daniel, Vasseur, Paule, Jacobs, Abigail, Aguila, M. Cecilia, Ertych, Norman, Jacobs, Miriam N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535778/
https://www.ncbi.nlm.nih.gov/pubmed/34681626
http://dx.doi.org/10.3390/ijms222010969

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