Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA

The processing of DNA double-strand breaks (DSBs) depends on the dynamic characteristics of chromatin. To investigate how abrupt changes in chromatin compaction alter these dynamics and affect DSB processing and repair, we exposed irradiated cells to hypotonic stress (HypoS). Densitometric and chrom...

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Detalles Bibliográficos
Autores principales: Krieger, Lisa Marie, Mladenov, Emil, Soni, Aashish, Demond, Marilen, Stuschke, Martin, Iliakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535785/
https://www.ncbi.nlm.nih.gov/pubmed/34681628
http://dx.doi.org/10.3390/ijms222010957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535785/
https://www.ncbi.nlm.nih.gov/pubmed/34681628
http://dx.doi.org/10.3390/ijms222010957

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