Cargando…

Preclinical Study of Immunological Isoxazole Derivatives as a Potential Support for Melanoma Chemotherapy

(1) Background: Melanoma is an aggressive neoplasm derived from melanocyte precursors with a high metastatic potential. Responses to chemotherapy and immunotherapy for melanoma remain weak, underlining the urgent need to develop new therapeutic strategies for the treatment of melanoma. (2) Methods:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jęśkowiak, Izabela, Wiatrak, Benita, Szeląg, Adam, Mączyński, Marcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535817/ https://www.ncbi.nlm.nih.gov/pubmed/34681580 http://dx.doi.org/10.3390/ijms222010920

Ejemplares similares

Patients’ Habits and the Role of Pharmacists and Telemedicine as Elements of a Modern Health Care System during the COVID-19 Pandemic
por: Grosman-Dziewiszek, Patrycja, et al.
Publicado: (2021)

The Incidence and Severity of Post-Vaccination Reactions after Vaccination against COVID-19
por: Jęśkowiak, Izabela, et al.
Publicado: (2021)

Does Inflammation Play a Major Role in the Pathogenesis of Alzheimer's Disease?
por: Wiatrak, Benita, et al.
Publicado: (2023)

New Oxazolo[5,4-d]pyrimidines as Potential Anticancer Agents: Their Design, Synthesis, and In Vitro Biological Activity Research
por: Sochacka-Ćwikła, Aleksandra, et al.
Publicado: (2022)

The Role of the Microbiota-Gut-Brain Axis in the Development of Alzheimer’s Disease
por: Wiatrak, Benita, et al.
Publicado: (2022)

Isoxazole Derivatives as Regulators of Immune Functions
por: Zimecki, Michał, et al.
Publicado: (2018)

Investigation of the Properties of Linen Fibers and Dressings
por: Gębarowski, Tomasz, et al.
Publicado: (2022)

The In Vitro Impact of Isoxazole Derivatives on Pathogenic Biofilm and Cytotoxicity of Fibroblast Cell Line
por: Bąchor, Urszula, et al.
Publicado: (2023)

Oils from Transgenic Flax Lines as Potential Chemopreventive Agents in Colorectal Cancer
por: Gębarowski, Tomasz, et al.
Publicado: (2023)

Synthesis, Immunosuppressive Properties, and Mechanism of Action of a New Isoxazole Derivative
por: Mączyński, Marcin, et al.
Publicado: (2018)

The N’-Substituted Derivatives of 5-Chloro-3-Methylisothiazole-4-Carboxylic Acid Hydrazide with Antiproliferative Activity
por: Jęśkowiak, Izabela, et al.
Publicado: (2019)

The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties
por: Gębarowski, Tomasz, et al.
Publicado: (2021)

New water-soluble isoxazole-linked 1,3,4-oxadiazole derivative with delocalized positive charge
por: Bąchor, Urszula, et al.
Publicado: (2021)

Design, Synthesis, Biological Evaluation, and Molecular Docking Study of 4,6-Dimethyl-5-aryl/alkyl-2-[2-hydroxy-3-(4-substituted-1-piperazinyl)propyl]pyrrolo[3,4-c]pyrrole-1,3(2H,5H)-diones as Anti-Inflammatory Agents with Dual Inhibition of COX and LOX
por: Redzicka, Aleksandra, et al.
Publicado: (2023)

Sanguinarine-Chelerythrine Fraction of Coptis chinensis Exerts Anti-inflammatory Activity in Carrageenan Paw Oedema Test in Rats and Reveals Reduced Gastrotoxicity
por: Danielewski, Maciej, et al.
Publicado: (2022)

The Risk of Developing Alzheimer’s Disease and Parkinson’s Disease in Patients with Inflammatory Bowel Disease: A Meta-Analysis
por: Szandruk-Bender, Marta, et al.
Publicado: (2022)

Antimicrobial and Cytotoxic Activities of Water-Soluble Isoxazole-Linked 1,3,4-Oxadiazole with Delocalized Charge: In Vitro and In Vivo Results
por: Dudek, Bartłomiej, et al.
Publicado: (2023)

Effect of tricyclic 1,2-thiazine derivatives in neuroinflammation induced by preincubation with lipopolysaccharide or coculturing with microglia-like cells
por: Wiatrak, Benita, et al.
Publicado: (2022)

Bioactive Olivacine Derivatives—Potential Application in Cancer Therapy
por: Tylińska, Beata, et al.
Publicado: (2021)

5-Amino-3-methyl-Isoxazole-4-carboxylic Acid as a Novel Unnatural Amino Acid in the Solid Phase Synthesis of α/β-Mixed Peptides
por: Bąchor, Urszula, et al.
Publicado: (2022)

Targeting Lineage-Specific Transcription Factors and Cytokines of the Th17/Treg Axis by Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone Attenuates TNBS-Induced Experimental Colitis
por: Szandruk-Bender, Marta, et al.
Publicado: (2022)

Synthesis and anti-nociceptive potential of isoxazole carboxamide derivatives
por: Bibi, Hajira, et al.
Publicado: (2019)

In vitro and in vivo assessment of the antioxidant potential of isoxazole derivatives
por: Hawash, Mohammed, et al.
Publicado: (2022)

Imatinib-Functionalized Galactose Hydrogels Loaded with Nanohydroxyapatite as a Drug Delivery System for Osteosarcoma: In Vitro Studies
por: Sobierajska, Paulina, et al.
Publicado: (2023)

Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]pyridazinone Exert Antinociceptive Activity in the Tail-Flick and Formalin Test in Rodents and Reveal Reduced Gastrotoxicity
por: Szandruk-Bender, Marta, et al.
Publicado: (2020)

Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced Rat Paw Edema Test
por: Szandruk-Bender, Marta, et al.
Publicado: (2021)

Long-Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats
por: Matuszewska, Agnieszka, et al.
Publicado: (2021)

Clean and Efficient Synthesis of Isoxazole Derivatives in Aqueous Media
por: Dou, Guolan, et al.
Publicado: (2013)

Isoxazole derivatives as new nitric oxide elicitors in plants
por: Oancea, Anca, et al.
Publicado: (2017)

Lewis acid-promoted direct synthesis of isoxazole derivatives
por: Qiu, Dengxu, et al.
Publicado: (2023)

Nanohydroxyapatite as a Biomaterial for Peripheral Nerve Regeneration after Mechanical Damage—In Vitro Study
por: Wiatrak, Benita, et al.
Publicado: (2021)

Novel Pyrimidine Derivatives as Potential Anticancer Agents: Synthesis, Biological Evaluation and Molecular Docking Study
por: Tylińska, Beata, et al.
Publicado: (2021)

The Hypothalamic-Pituitary-Gonadal Axis in Men with Schizophrenia
por: Matuszewska, Agnieszka, et al.
Publicado: (2023)

Influence of 40 Hz and 100 Hz Vibration on SH-SY5Y Cells Growth and Differentiation—A Preliminary Study
por: Grosman-Dziewiszek, Patrycja, et al.
Publicado: (2022)

Synthesis of novel isoxazole–carboxamide derivatives as promising agents for melanoma and targeted nano-emulgel conjugate for improved cellular permeability
por: Hawash, Mohammed, et al.
Publicado: (2022)

Synthesis and Antihypertensive Screening of New Derivatives of Quinazolines Linked with Isoxazole
por: Rahman, Mujeeb Ur, et al.
Publicado: (2014)

Selected β(2)-, β(3)- and β(2,3)-Amino Acid Heterocyclic Derivatives and Their Biological Perspective
por: Bąchor, Urszula, et al.
Publicado: (2021)

A DFT Study of Pyrrole-Isoxazole Derivatives as Chemosensors for Fluoride Anion
por: Jin, Ruifa, et al.
Publicado: (2012)

Synthesis, in-vitro inhibition of cyclooxygenases and in silico studies of new isoxazole derivatives
por: Alam, Waqas, et al.
Publicado: (2023)

Antitumor Activity of New Olivacine Derivatives
por: Piasny, Janusz, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cf40nrrokji7dfbq56c7k53umi