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Machine Learning to Identify Interaction of Single-Nucleotide Polymorphisms as a Risk Factor for Chronic Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is a major cause of drug development failure and drug withdrawal from the market after approval. The identification of human risk factors associated with susceptibility to DILI is of paramount importance. Increasing evidence suggests that genetic variants may lead to...

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Detalles Bibliográficos
Autores principales: Moore, Roland, Ashby, Kristin, Liao, Tsung-Jen, Chen, Minjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535865/
https://www.ncbi.nlm.nih.gov/pubmed/34682349
http://dx.doi.org/10.3390/ijerph182010603