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Could Cytochrome P450 2D6, 3A4 and 3A5 Polymorphisms Explain the Variability in Clinical Response to Clomiphene Citrate of Anovulatory PCOS Women?

INTRODUCTION: Cytochrome P450 2D6, 3A4 and 3A5 are involved in the metabolism of many drugs. These enzymes have a genetic polymorphism responsible for different metabolic phenotypes. They play a role in the metabolism of clomiphene citrate (CC), which is used to induce ovulation. Response to CC trea...

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Detalles Bibliográficos
Autores principales:	Robin, Camille, Hennart, Benjamin, Broly, Franck, Gruchala, Philippine, Robin, Geoffroy, Catteau-Jonard, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535872/ https://www.ncbi.nlm.nih.gov/pubmed/34690927 http://dx.doi.org/10.3389/fendo.2021.718917

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