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Molecular Mechanism of Food-Derived Polyphenols on PD-L1 Dimerization: A Molecular Dynamics Simulation Study

In cancer immunotherapy, an emerging approach is to block the interactions of programmed cell death-1 (PD-1) and programmed cell death-ligand 1 (PD-L1) using small-molecule inhibitors. The food-derived polyphenols curcumin (CC), resveratrol (RSV) and epigallocatechin gallate (EGCG) have anticancer i...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Liang, Jianhuai, Liu, Boping, Jin, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535905/
https://www.ncbi.nlm.nih.gov/pubmed/34681584
http://dx.doi.org/10.3390/ijms222010924

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