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Effects of Fine Particulate Matter and Its Components on Emergency Room Visits for Pediatric Pneumonia: A Time-Stratified Case-Crossover Study

Pneumonia, one of the important causes of death in children, may be induced or aggravated by particulate matter (PM). Limited research has examined the association between PM and its constituents and pediatric pneumonia-related emergency department (ED) visits. Measurements of PM(2.5), PM(10), and f...

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Autores principales: Tsai, Ming-Ta, Ho, Yu-Ni, Chiang, Charng-Yen, Chuang, Po-Chun, Pan, Hsiu-Yung, Chiu, I-Min, Tsai, Chih-Min, Cheng, Fu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535937/
https://www.ncbi.nlm.nih.gov/pubmed/34682345
http://dx.doi.org/10.3390/ijerph182010599
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author Tsai, Ming-Ta
Ho, Yu-Ni
Chiang, Charng-Yen
Chuang, Po-Chun
Pan, Hsiu-Yung
Chiu, I-Min
Tsai, Chih-Min
Cheng, Fu-Jen
author_facet Tsai, Ming-Ta
Ho, Yu-Ni
Chiang, Charng-Yen
Chuang, Po-Chun
Pan, Hsiu-Yung
Chiu, I-Min
Tsai, Chih-Min
Cheng, Fu-Jen
author_sort Tsai, Ming-Ta
collection PubMed
description Pneumonia, one of the important causes of death in children, may be induced or aggravated by particulate matter (PM). Limited research has examined the association between PM and its constituents and pediatric pneumonia-related emergency department (ED) visits. Measurements of PM(2.5), PM(10), and four PM(2.5) constituents, including elemental carbon (EC), organic carbon (OC), nitrate, and sulfate, were extracted from 2007 to 2010 from one core station and two satellite stations in Kaohsiung City, Taiwan. Furthermore, the medical records of patients under 17 years old who had visited the ED in a medical center and had a diagnosis of pneumonia were collected. We used a time-stratified, case-crossover study design to estimate the effect of PM. The single-pollutant model demonstrated interquartile range increase in PM(2.5), PM(10), nitrate, OC, and EC on lag 3, which increased the risk of pediatric pneumonia by 18.2% (95% confidence interval (Cl), 8.8–28.4%), 13.1% (95% CI, 5.1–21.7%), 29.7% (95% CI, 16.4–44.5%), 16.8% (95% CI, 4.6–30.4%), and 14.4% (95% Cl, 6.5–22.9%), respectively. After PM(2.5), PM(10), and OC were adjusted for, nitrate and EC remained significant in two-pollutant models. Subgroup analyses revealed that nitrate had a greater effect on children during the warm season (April to September, interaction p = 0.035). In conclusion, pediatric pneumonia ED visit was related to PM(2.5) and its constituents. Moreover, PM(2.5) constituents, nitrate and EC, were more closely associated with ED visits for pediatric pneumonia, and children seemed to be more susceptible to nitrate during the warm season.
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spelling pubmed-85359372021-10-23 Effects of Fine Particulate Matter and Its Components on Emergency Room Visits for Pediatric Pneumonia: A Time-Stratified Case-Crossover Study Tsai, Ming-Ta Ho, Yu-Ni Chiang, Charng-Yen Chuang, Po-Chun Pan, Hsiu-Yung Chiu, I-Min Tsai, Chih-Min Cheng, Fu-Jen Int J Environ Res Public Health Article Pneumonia, one of the important causes of death in children, may be induced or aggravated by particulate matter (PM). Limited research has examined the association between PM and its constituents and pediatric pneumonia-related emergency department (ED) visits. Measurements of PM(2.5), PM(10), and four PM(2.5) constituents, including elemental carbon (EC), organic carbon (OC), nitrate, and sulfate, were extracted from 2007 to 2010 from one core station and two satellite stations in Kaohsiung City, Taiwan. Furthermore, the medical records of patients under 17 years old who had visited the ED in a medical center and had a diagnosis of pneumonia were collected. We used a time-stratified, case-crossover study design to estimate the effect of PM. The single-pollutant model demonstrated interquartile range increase in PM(2.5), PM(10), nitrate, OC, and EC on lag 3, which increased the risk of pediatric pneumonia by 18.2% (95% confidence interval (Cl), 8.8–28.4%), 13.1% (95% CI, 5.1–21.7%), 29.7% (95% CI, 16.4–44.5%), 16.8% (95% CI, 4.6–30.4%), and 14.4% (95% Cl, 6.5–22.9%), respectively. After PM(2.5), PM(10), and OC were adjusted for, nitrate and EC remained significant in two-pollutant models. Subgroup analyses revealed that nitrate had a greater effect on children during the warm season (April to September, interaction p = 0.035). In conclusion, pediatric pneumonia ED visit was related to PM(2.5) and its constituents. Moreover, PM(2.5) constituents, nitrate and EC, were more closely associated with ED visits for pediatric pneumonia, and children seemed to be more susceptible to nitrate during the warm season. MDPI 2021-10-10 /pmc/articles/PMC8535937/ /pubmed/34682345 http://dx.doi.org/10.3390/ijerph182010599 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tsai, Ming-Ta
Ho, Yu-Ni
Chiang, Charng-Yen
Chuang, Po-Chun
Pan, Hsiu-Yung
Chiu, I-Min
Tsai, Chih-Min
Cheng, Fu-Jen
Effects of Fine Particulate Matter and Its Components on Emergency Room Visits for Pediatric Pneumonia: A Time-Stratified Case-Crossover Study
title Effects of Fine Particulate Matter and Its Components on Emergency Room Visits for Pediatric Pneumonia: A Time-Stratified Case-Crossover Study
title_full Effects of Fine Particulate Matter and Its Components on Emergency Room Visits for Pediatric Pneumonia: A Time-Stratified Case-Crossover Study
title_fullStr Effects of Fine Particulate Matter and Its Components on Emergency Room Visits for Pediatric Pneumonia: A Time-Stratified Case-Crossover Study
title_full_unstemmed Effects of Fine Particulate Matter and Its Components on Emergency Room Visits for Pediatric Pneumonia: A Time-Stratified Case-Crossover Study
title_short Effects of Fine Particulate Matter and Its Components on Emergency Room Visits for Pediatric Pneumonia: A Time-Stratified Case-Crossover Study
title_sort effects of fine particulate matter and its components on emergency room visits for pediatric pneumonia: a time-stratified case-crossover study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535937/
https://www.ncbi.nlm.nih.gov/pubmed/34682345
http://dx.doi.org/10.3390/ijerph182010599
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