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PACAP and VIP Modulate LPS-Induced Microglial Activation and Trigger Distinct Phenotypic Changes in Murine BV2 Microglial Cells

Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are two structurally related immunosuppressive peptides. However, the underlying mechanisms through which these peptides regulate microglial activity are not fully understood. Using lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: Karunia, Jocelyn, Niaz, Aram, Mandwie, Mawj, Thomas Broome, Sarah, Keay, Kevin A., Waschek, James A., Al-Badri, Ghaith, Castorina, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535941/
https://www.ncbi.nlm.nih.gov/pubmed/34681607
http://dx.doi.org/10.3390/ijms222010947