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Haemophilic Pelvic Pseudotumour: A New Surgical Option
Background: Haemophilia is an inherited coagulopathy caused by the absence or dysfunction of clotting factor VIII or IX. Clinical manifestations are generally secondary to recurrent bleeding episodes mainly in the musculoskeletal system. Bleeding symptoms appear early in life and, when the disease i...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536013/ https://www.ncbi.nlm.nih.gov/pubmed/34682949 http://dx.doi.org/10.3390/healthcare9101269 |
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author | Pasta, Gianluigi Ruggieri, Roberta Annunziata, Salvatore Gallese, Alessandro Gagliardi, Vincenzo Pio Cuzzocrea, Fabrizio Ghiara, Matteo Russo, Mariaconcetta Preti, Paola Stefania Santi, Roberto Mario Mosconi, Mario Benazzo, Francesco |
author_facet | Pasta, Gianluigi Ruggieri, Roberta Annunziata, Salvatore Gallese, Alessandro Gagliardi, Vincenzo Pio Cuzzocrea, Fabrizio Ghiara, Matteo Russo, Mariaconcetta Preti, Paola Stefania Santi, Roberto Mario Mosconi, Mario Benazzo, Francesco |
author_sort | Pasta, Gianluigi |
collection | PubMed |
description | Background: Haemophilia is an inherited coagulopathy caused by the absence or dysfunction of clotting factor VIII or IX. Clinical manifestations are generally secondary to recurrent bleeding episodes mainly in the musculoskeletal system. Bleeding symptoms appear early in life and, when the disease is severe (when plasma factor VIII or IX activity is <1% of normal), joint and muscle bleeding may occur spontaneously. A pseudotumour is a recurrent, chronic, encapsulated, slowly expanding, muscle hematoma. Haemophilic pseudotumour is a rare complication of haemophilia which occurs, as a condition either from repeated spontaneous bleeding or coming from a traumatic origin, in 1–2% of haemophilic patients. Case report: A 32-year-old man with severe haemophilia A referred to our Clinic with a massive right iliac wing pseudotumour complicated by Staphylococcus aureus superinfection and skin fistulisation. In this report we describe the medical management and surgical treatment by the adoption of a novel surgical technique which involves the use of a pedicle-screw and rod system (PSRS), a polyglycolic acid MESH and bone cement in order to build up an artificial ilium-like bony mass. This case report highlights the importance of interdisciplinary approach and the efficacy of eradicating surgery as treatment, especially in the case of large and long-lasting lesions. |
format | Online Article Text |
id | pubmed-8536013 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85360132021-10-23 Haemophilic Pelvic Pseudotumour: A New Surgical Option Pasta, Gianluigi Ruggieri, Roberta Annunziata, Salvatore Gallese, Alessandro Gagliardi, Vincenzo Pio Cuzzocrea, Fabrizio Ghiara, Matteo Russo, Mariaconcetta Preti, Paola Stefania Santi, Roberto Mario Mosconi, Mario Benazzo, Francesco Healthcare (Basel) Case Report Background: Haemophilia is an inherited coagulopathy caused by the absence or dysfunction of clotting factor VIII or IX. Clinical manifestations are generally secondary to recurrent bleeding episodes mainly in the musculoskeletal system. Bleeding symptoms appear early in life and, when the disease is severe (when plasma factor VIII or IX activity is <1% of normal), joint and muscle bleeding may occur spontaneously. A pseudotumour is a recurrent, chronic, encapsulated, slowly expanding, muscle hematoma. Haemophilic pseudotumour is a rare complication of haemophilia which occurs, as a condition either from repeated spontaneous bleeding or coming from a traumatic origin, in 1–2% of haemophilic patients. Case report: A 32-year-old man with severe haemophilia A referred to our Clinic with a massive right iliac wing pseudotumour complicated by Staphylococcus aureus superinfection and skin fistulisation. In this report we describe the medical management and surgical treatment by the adoption of a novel surgical technique which involves the use of a pedicle-screw and rod system (PSRS), a polyglycolic acid MESH and bone cement in order to build up an artificial ilium-like bony mass. This case report highlights the importance of interdisciplinary approach and the efficacy of eradicating surgery as treatment, especially in the case of large and long-lasting lesions. MDPI 2021-09-26 /pmc/articles/PMC8536013/ /pubmed/34682949 http://dx.doi.org/10.3390/healthcare9101269 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Pasta, Gianluigi Ruggieri, Roberta Annunziata, Salvatore Gallese, Alessandro Gagliardi, Vincenzo Pio Cuzzocrea, Fabrizio Ghiara, Matteo Russo, Mariaconcetta Preti, Paola Stefania Santi, Roberto Mario Mosconi, Mario Benazzo, Francesco Haemophilic Pelvic Pseudotumour: A New Surgical Option |
title | Haemophilic Pelvic Pseudotumour: A New Surgical Option |
title_full | Haemophilic Pelvic Pseudotumour: A New Surgical Option |
title_fullStr | Haemophilic Pelvic Pseudotumour: A New Surgical Option |
title_full_unstemmed | Haemophilic Pelvic Pseudotumour: A New Surgical Option |
title_short | Haemophilic Pelvic Pseudotumour: A New Surgical Option |
title_sort | haemophilic pelvic pseudotumour: a new surgical option |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536013/ https://www.ncbi.nlm.nih.gov/pubmed/34682949 http://dx.doi.org/10.3390/healthcare9101269 |
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