Evaluating the Immunomodulatory Profile and Treatment Efficacy of Whole Lung Low-Dose Radiation Therapy (LDRT) in a Preclinical Model of Severe Viral Pneumonia

PURPOSE/OBJECTIVE(S): Whole Lung Low-Dose Radiation Therapy (LDRT) is currently being tested as a treatment for SARS-CoV-2. Whether LDRT alters the natural history of viral infection, lung microenvironment or host immunity is currently unknown. We developed a preclinical model of severe viral pneumo...

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Detalles Bibliográficos
Autores principales: Dhanota, N., Pilones, K.A., Kraynak, J., Demaria, S., Formenti, S.C., Salvatore, M., Marciscano, A.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
2470
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536242/
http://dx.doi.org/10.1016/j.ijrobp.2021.07.805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536242/
http://dx.doi.org/10.1016/j.ijrobp.2021.07.805

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