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Evaluating the Immunomodulatory Profile and Treatment Efficacy of Whole Lung Low-Dose Radiation Therapy (LDRT) in a Preclinical Model of Severe Viral Pneumonia
PURPOSE/OBJECTIVE(S): Whole Lung Low-Dose Radiation Therapy (LDRT) is currently being tested as a treatment for SARS-CoV-2. Whether LDRT alters the natural history of viral infection, lung microenvironment or host immunity is currently unknown. We developed a preclinical model of severe viral pneumo...
Autores principales: | Dhanota, N., Pilones, K.A., Kraynak, J., Demaria, S., Formenti, S.C., Salvatore, M., Marciscano, A.E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536242/ http://dx.doi.org/10.1016/j.ijrobp.2021.07.805 |
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