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SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice
Calcineurin is a calcium-dependent phosphatase that plays roles in a variety of biological processes including immune responses. In spermatozoa, there is a testis-enriched calcineurin composed of PPP3CC and PPP3R2 (sperm calcineurin) that is essential for sperm motility and male fertility. Because s...
Autores principales: | Miyata, Haruhiko, Oura, Seiya, Morohoshi, Akane, Shimada, Keisuke, Mashiko, Daisuke, Oyama, Yuki, Kaneda, Yuki, Matsumura, Takafumi, Abbasi, Ferheen, Ikawa, Masahito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536318/ https://www.ncbi.nlm.nih.gov/pubmed/34446558 http://dx.doi.org/10.1073/pnas.2106673118 |
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