Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer

Cellular senescence causes a dramatic alteration of chromatin organization and changes the gene expression profile of proinflammatory factors, thereby contributing to various age-related pathologies through the senescence-associated secretory phenotype (SASP). Chromatin organization and global gene...

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Detalles Bibliográficos
Autores principales: Miyata, Kenichi, Imai, Yoshinori, Hori, Satoshi, Nishio, Mika, Loo, Tze Mun, Okada, Ryo, Yang, Liying, Nakadai, Tomoyoshi, Maruyama, Reo, Fujii, Risa, Ueda, Koji, Jiang, Li, Zheng, Hao, Toyokuni, Shinya, Sakata, Toyonori, Shirahige, Katsuhiko, Kojima, Ryosuke, Nakayama, Mizuho, Oshima, Masanobu, Nagayama, Satoshi, Seimiya, Hiroyuki, Hirota, Toru, Saya, Hideyuki, Hara, Eiji, Takahashi, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536346/
https://www.ncbi.nlm.nih.gov/pubmed/34426493
http://dx.doi.org/10.1073/pnas.2025647118

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