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The LpoA activator is required to stimulate the peptidoglycan polymerase activity of its cognate cell wall synthase PBP1a
A cell wall made of the heteropolymer peptidoglycan (PG) surrounds most bacterial cells. This essential surface layer is required to prevent lysis from internal osmotic pressure. The class A penicillin-binding proteins (aPBPs) play key roles in building the PG network. These bifunctional enzymes pos...
Autores principales: | Sardis, Marios F., Bohrhunter, Jessica L., Greene, Neil G., Bernhardt, Thomas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536351/ https://www.ncbi.nlm.nih.gov/pubmed/34429361 http://dx.doi.org/10.1073/pnas.2108894118 |
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