Cargando…

Exosomes Derived from miR-146a-5p-Enriched Mesenchymal Stem Cells Protect the Cardiomyocytes and Myocardial Tissues in the Polymicrobial Sepsis through Regulating MYBL1

BACKGROUND: At present, the study has confirmed that the mesenchymal stem cell-derived exosomes (MCSs-Exo) possess cardio-protection in sepsis. Nevertheless, the molecular mechanism of the protection of MSCs-Exo in sepsis remains unknown. Therefore, this research is aimed at studying the molecular m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Chun, Xue, Jianhua, Xu, Bo, Zhang, Aixian, Qin, Lili, Liu, Jiajia, Yang, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536448/ https://www.ncbi.nlm.nih.gov/pubmed/34691188 http://dx.doi.org/10.1155/2021/1530445

Ejemplares similares

Exosomal miR-223 Contributes to Mesenchymal Stem Cell-Elicited Cardioprotection in Polymicrobial Sepsis
por: Wang, Xiaohong, et al.
Publicado: (2015)

Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis
por: Yang, Kun, et al.
Publicado: (2021)

Modulation of Myocardial Mitochondrial Mechanisms during Severe Polymicrobial Sepsis in the Rat
por: Chopra, Mani, et al.
Publicado: (2011)

Novel Role of Endothelial Derived Exosomal HSPA12B in Regulating Macrophage Inflammatory Responses in Polymicrobial Sepsis
por: Tu, Fei, et al.
Publicado: (2020)

Mesenchymal stem cell-derived exosomal miR-146a reverses diabetic β-cell dedifferentiation
por: He, Qin, et al.
Publicado: (2021)

Role of Cardiomyocyte-Derived Exosomal MicroRNA-146a-5p in Macrophage Polarization and Activation
por: Chen, Cong, et al.
Publicado: (2022)

LncRNA KCNQ10T1 shuttled by bone marrow mesenchymal stem cell-derived exosome inhibits sepsis via regulation of miR-154-3p/RNF19A axis
por: Yuan, Haojie, et al.
Publicado: (2023)

Outcome of unimicrobial versus polymicrobial sepsis
por: Abed, N, et al.
Publicado: (2010)

Retraction Note: Mesenchymal stem cell-derived exosomal miR-146a reverses diabetic β-cell dedifferentiation
por: He, Qin, et al.
Publicado: (2022)

Role of the membrane receptor ALXR in polymicrobial sepsis
por: Silva, LC Resende, et al.
Publicado: (2012)

Metagenomic evidence for a polymicrobial signature of sepsis
por: Tan, Cedric Chih Shen, et al.
Publicado: (2021)

Molecular Methodologies for Improved Polymicrobial Sepsis Diagnosis
por: Doualeh, Mariam, et al.
Publicado: (2022)

A MYBL2 complex for RRM2 transactivation and the synthetic effect of MYBL2 knockdown with WEE1 inhibition against colorectal cancer
por: Liu, Qian, et al.
Publicado: (2021)

Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming
por: Ward, Carl, et al.
Publicado: (2018)

Cathelicidin preserves intestinal barrier function in polymicrobial sepsis
por: Ho, Jeffery, et al.
Publicado: (2020)

Sinomenine Hydrochloride Protects against Polymicrobial Sepsis via Autophagy
por: Jiang, Yu, et al.
Publicado: (2015)

The Functional Polymorphisms of miR-146a Are Associated with Susceptibility to Severe Sepsis in the Chinese Population
por: Shao, Yiming, et al.
Publicado: (2014)

Mybl2 rejuvenates heart explant‐derived cells from aged donors after myocardial infarction
por: Rafatian, Ghazaleh, et al.
Publicado: (2020)

Multiple Myeloma-Derived Exosomes Regulate the Functions of Mesenchymal Stem Cells Partially via Modulating miR-21 and miR-146a
por: Cheng, Qian, et al.
Publicado: (2017)

An enriched environment prevents diabetes-induced cognitive impairment in rats by enhancing exosomal miR-146a secretion from endogenous bone marrow-derived mesenchymal stem cells
por: Kubota, Kenta, et al.
Publicado: (2018)

Modulatory Effects of Astragalus Polysaccharides on T-Cell Polarization in Mice with Polymicrobial Sepsis
por: Hou, Yu-Chen, et al.
Publicado: (2015)

Mesenchymal Stem/Stromal Cells Increase Cardiac miR-187-3p Expression in a Polymicrobial Animal Model of Sepsis
por: Ektesabi, Amin M., et al.
Publicado: (2021)

Circulating Exosomes Derived-miR-146a from Systemic Lupus Erythematosus Patients Regulates Senescence of Mesenchymal Stem Cells
por: Dong, Chen, et al.
Publicado: (2019)

SLAMF7 regulates the inflammatory response in macrophages during polymicrobial sepsis
por: Wu, Yongjian, et al.
Publicado: (2023)

miR-146a inhibits mitochondrial dysfunction and myocardial infarction by targeting cyclophilin D
por: Su, Qiang, et al.
Publicado: (2021)

Polymicrobial Sepsis in an Immunocompetent Host due to Self Injection of Urine
por: Subramanian, Senthilkumaran, et al.
Publicado: (2011)

The role of CC-chemokine receptor 4 in murine polymicrobial sepsis
por: Maier, Stefan, et al.
Publicado: (2007)

Peroxynitrite mediates neutrophil migration failure in severe polymicrobial sepsis
por: Dal-Secco, Daniela, et al.
Publicado: (2007)

IL-17 receptor signaling is required to control polymicrobial sepsis
por: Freitas, A
Publicado: (2009)

Aryl hydrocarbon receptor activation increases survival in polymicrobial sepsis
por: de Freitas, A, et al.
Publicado: (2014)

Protective Role of Hepcidin in Polymicrobial Sepsis and Acute Kidney Injury
por: Scindia, Yogesh, et al.
Publicado: (2019)

Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis
por: Souza, Maria C., et al.
Publicado: (2017)

Antibody Production in Murine Polymicrobial Sepsis—Kinetics and Key Players
por: Nicolai, Oliver, et al.
Publicado: (2020)

Polymerized albumin restores impaired hemodynamics in endotoxemia and polymicrobial sepsis
por: Belcher, Donald A., et al.
Publicado: (2021)

Serial Change of Endotoxin Tolerance in a Polymicrobial Sepsis Model
por: Lee, Min Ji, et al.
Publicado: (2022)

Effects of Mitochondrial Transplantation on Transcriptomics in a Polymicrobial Sepsis Model
por: Kim, Seongmin, et al.
Publicado: (2023)

LncRNA NEAT1 Promotes Inflammatory Response in Sepsis via the miR-31-5p/POU2F1 Axis
por: Yang, Yang, et al.
Publicado: (2021)

Extracellular miR-146a-5p Induces Cardiac Innate Immune Response and Cardiomyocyte Dysfunction
por: Shimada, Briana K., et al.
Publicado: (2020)

MYB/MYBL1::QKI fusion-positive diffuse glioma
por: Suh, Ye Yoon, et al.
Publicado: (2023)

MYBL2 Gene Polymorphism Is Associated With Acute Lymphoblastic Leukemia Susceptibility in Children
por: Guo, Haixia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jji2gl5j975qjuj8oui4rf1a5o