Cargando…
Suppression of endothelial miR-22 mediates non-small cell lung cancer cell-induced angiogenesis
MicroRNAs (miRNAs) expressed in endothelial cells (ECs) are powerful regulators of angiogenesis, which is essential for tumor growth and metastasis. Here, we demonstrated that miR-22 is preferentially and highly expressed in ECs, while its endothelial level is significantly downregulated in human no...
Autores principales: | Gu, Yuan, Pais, Gianni, Becker, Vivien, Körbel, Christina, Ampofo, Emmanuel, Ebert, Elke, Hohneck, Johannes, Ludwig, Nicole, Meese, Eckart, Bohle, Rainer M., Zhao, Yingjun, Menger, Michael D., Laschke, Matthias W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536510/ https://www.ncbi.nlm.nih.gov/pubmed/34729252 http://dx.doi.org/10.1016/j.omtn.2021.10.003 |
Ejemplares similares
-
Hypoxia-induced downregulation of microRNA-186-5p in endothelial cells promotes non-small cell lung cancer angiogenesis by upregulating protein kinase C alpha
por: Becker, Vivien, et al.
Publicado: (2023) -
Brassinin Promotes the Degradation of Tie2 and FGFR1 in Endothelial Cells and Inhibits Triple-Negative Breast Cancer Angiogenesis
por: Gu, Yuan, et al.
Publicado: (2022) -
Linalool inhibits the angiogenic activity of endothelial cells by downregulating intracellular ATP levels and activating TRPM8
por: Becker, Vivien, et al.
Publicado: (2021) -
MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2
por: Werner, Tamara V., et al.
Publicado: (2017) -
Tubeimoside-1 suppresses tumor angiogenesis by stimulation of proteasomal VEGFR2 and Tie2 degradation in a non-small cell lung cancer xenograft model
por: Gu, Yuan, et al.
Publicado: (2015)