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A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates
Activation of nucleic acid sensing Toll-like receptors (TLRs) in B cells is involved in antiviral responses by promoting B cell activation and germinal center responses. In order to take advantage of this natural pathway for vaccine development, synthetic pathogen-like antigens (PLAs) constructed of...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536523/ https://www.ncbi.nlm.nih.gov/pubmed/34723223 http://dx.doi.org/10.1016/j.xcrm.2021.100448 |