A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates

Activation of nucleic acid sensing Toll-like receptors (TLRs) in B cells is involved in antiviral responses by promoting B cell activation and germinal center responses. In order to take advantage of this natural pathway for vaccine development, synthetic pathogen-like antigens (PLAs) constructed of...

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Detalles Bibliográficos
Autores principales: Guo, Chang, Peng, Yanan, Lin, Lin, Pan, Xiaoyan, Fang, Mengqi, Zhao, Yun, Bao, Keyan, Li, Runhan, Han, Jianbao, Chen, Jiaorong, Song, Tian-Zhang, Feng, Xiao-Li, Zhou, Yahong, Zhao, Gan, Zhang, Leike, Zheng, Yongtang, Zhu, Ping, Hang, Haiying, Zhang, Linqi, Hua, Zhaolin, Deng, Hongyu, Hou, Baidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536523/
https://www.ncbi.nlm.nih.gov/pubmed/34723223
http://dx.doi.org/10.1016/j.xcrm.2021.100448

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