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Modulating expression of inhibitory and stimulatory immune ‘checkpoints’ using nanoparticulate-assisted nucleic acid delivery

Immune checkpoints are regulatory molecules responsible for determining the magnitude and nature of the immune response. The aim of immune checkpoint targeting immunotherapy is to manipulate these interactions, engaging the immune system in treatment of cancer. Clinically, the use of monoclonal anti...

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Detalles Bibliográficos
Autores principales: Walters, Adam A, Dhadwar, Baljevan, Al-Jamal, Khuloud T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536530/
https://www.ncbi.nlm.nih.gov/pubmed/34688033
http://dx.doi.org/10.1016/j.ebiom.2021.103624

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