Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling

Several neonicotinoids have recently been shown to activate the nicotinic acetylcholine receptor (nAChR) on human neurons. Moreover, imidacloprid (IMI) and other members of this pesticide family form a set of diverse metabolites within crops. Among these, desnitro-imidacloprid (DN-IMI) is of special...

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Detalles Bibliográficos
Autores principales: Loser, Dominik, Grillberger, Karin, Hinojosa, Maria G., Blum, Jonathan, Haufe, Yves, Danker, Timm, Johansson, Ylva, Möller, Clemens, Nicke, Annette, Bennekou, Susanne H., Gardner, Iain, Bauch, Caroline, Walker, Paul, Forsby, Anna, Ecker, Gerhard F., Kraushaar, Udo, Leist, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Molecular Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536575/
https://www.ncbi.nlm.nih.gov/pubmed/34628512
http://dx.doi.org/10.1007/s00204-021-03168-z

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