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Human placental extract ameliorates methotrexate-induced hepatotoxicity in rats via regulating antioxidative and anti-inflammatory responses

PURPOSE: Methotrexate (MTX) induces hepatotoxicity, limiting its clinical efficacy as a widely known chemotherapy drug. In the current study, we examined the protective effect of human placenta extract (HPE) against MTX-induced liver damage in rats, as well as its ability to regulate antioxidative a...

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Detalles Bibliográficos
Autores principales:	Ghoneum, Mamdooh, El-Gerbed, Mohamed S. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536621/ https://www.ncbi.nlm.nih.gov/pubmed/34505929 http://dx.doi.org/10.1007/s00280-021-04349-4

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