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The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment

Mechanism-based risk assessment is urged to advance and fully permeate into current safety assessment practices, possibly at early phases of drug safety testing. Toxicogenomics is a promising source of mechanisms-revealing data, but interpretative analysis tools specific for the testing systems (e.g...

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Detalles Bibliográficos
Autores principales: Callegaro, Giulia, Kunnen, Steven J., Trairatphisan, Panuwat, Grosdidier, Solène, Niemeijer, Marije, den Hollander, Wouter, Guney, Emre, Piñero Gonzalez, Janet, Furlong, Laura, Webster, Yue W., Saez-Rodriguez, Julio, Sutherland, Jeffrey J., Mollon, Jennifer, Stevens, James L., van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536636/
https://www.ncbi.nlm.nih.gov/pubmed/34626214
http://dx.doi.org/10.1007/s00204-021-03141-w