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CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis
The chromatin remodeler CHD8, which belongs to the ATP-dependent chromatin remodelers CHD family, is one of the most high-risk mutated genes in autism spectrum disorders. However, the role of CHD8 in neural differentiation and the mechanism of CHD8 in autism remains unclear, despite there are a few...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536677/ https://www.ncbi.nlm.nih.gov/pubmed/34686651 http://dx.doi.org/10.1038/s41419-021-04292-5 |