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A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase

The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in microbiome composition to invade its human host, causing pathologies ranging from vaginal candidiasis to fungal sepsis. Bacteria of the genus Lactobacillus are colonizers of human mucosa and can produce compounds...

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Detalles Bibliográficos
Autores principales:	MacAlpine, Jessie, Daniel-Ivad, Martin, Liu, Zhongle, Yano, Junko, Revie, Nicole M., Todd, Robert T., Stogios, Peter J., Sanchez, Hiram, O’Meara, Teresa R., Tompkins, Thomas A., Savchenko, Alexei, Selmecki, Anna, Veri, Amanda O., Andes, David R., Fidel, Paul L., Robbins, Nicole, Nodwell, Justin, Whitesell, Luke, Cowen, Leah E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536679/ https://www.ncbi.nlm.nih.gov/pubmed/34686660 http://dx.doi.org/10.1038/s41467-021-26390-w

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