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Smooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis

Vascular smooth muscle cells (VSMCs) are indispensable components in foam cell formation in atherosclerosis. However, the mechanism behind foam cell formation of VSMCs has not been addressed. We found a potential association between deletion of smooth muscle (SM) 22α and deregulated nuclear receptor...

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Detalles Bibliográficos
Autores principales: Zhang, Dan-Dan, Song, Yu, Kong, Peng, Xu, Xin, Gao, Ya-Kun, Dou, Yong-Qing, Weng, Lin, Wang, Xiao-Wei, Lin, Yan-Ling, Zhang, Fan, Zhang, Hailin, Han, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536684/
https://www.ncbi.nlm.nih.gov/pubmed/34686657
http://dx.doi.org/10.1038/s41419-021-04239-w