Swim training affects Akt signaling and ameliorates loss of skeletal muscle mass in a mouse model of amyotrophic lateral sclerosis

We tested the hypothesis that swim training reverses the impairment of Akt/FOXO3a signaling, ameliorating muscle atrophy in ALS mice. Transgenic male mice B6SJL-Tg (SOD1(G93A)) 1Gur/J were used as the ALS model (n = 35), with wild-type B6SJL (WT) mice as controls (n = 7). ALS mice were analyzed befo...

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Detalles Bibliográficos
Autores principales: Cieminski, Karol, Flis, Damian Jozef, Dzik, Katarzyna, Kaczor, Jan Jacek, Czyrko, Emilia, Halon-Golabek, Malgorzata, Wieckowski, Mariusz Roman, Antosiewicz, Jedrzej, Ziolkowski, Wieslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536703/
https://www.ncbi.nlm.nih.gov/pubmed/34686697
http://dx.doi.org/10.1038/s41598-021-00319-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536703/
https://www.ncbi.nlm.nih.gov/pubmed/34686697
http://dx.doi.org/10.1038/s41598-021-00319-1

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