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Characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery

BACKGROUND AND PURPOSE: Synthetic diamond detectors offer real time measurement of dose in radiotherapy applications which require high spatial resolution. Additional considerations and corrections are required for measurements where the diamond detector is orientated at various angles to the incide...

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Autores principales: Shaw, Maddison, Lye, Jessica, Alves, Andrew, Keehan, Stephanie, Lehmann, Joerg, Hanlon, Maximilian, Kenny, John, Baines, John, Porumb, Claudiu, Geso, Moshi, Brown, Rhonda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536779/
https://www.ncbi.nlm.nih.gov/pubmed/34722939
http://dx.doi.org/10.1016/j.phro.2021.10.002
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author Shaw, Maddison
Lye, Jessica
Alves, Andrew
Keehan, Stephanie
Lehmann, Joerg
Hanlon, Maximilian
Kenny, John
Baines, John
Porumb, Claudiu
Geso, Moshi
Brown, Rhonda
author_facet Shaw, Maddison
Lye, Jessica
Alves, Andrew
Keehan, Stephanie
Lehmann, Joerg
Hanlon, Maximilian
Kenny, John
Baines, John
Porumb, Claudiu
Geso, Moshi
Brown, Rhonda
author_sort Shaw, Maddison
collection PubMed
description BACKGROUND AND PURPOSE: Synthetic diamond detectors offer real time measurement of dose in radiotherapy applications which require high spatial resolution. Additional considerations and corrections are required for measurements where the diamond detector is orientated at various angles to the incident beam. This study investigated diamond detectors for end-to-end testing of Stereotactic Body Radiotherapy (SBRT) and Stereotactic Radiosurgery (SRS) in the context of dosimetry audits. MATERIAL AND METHODS: Seven individual diamond detectors were investigated and compared with respect to warm up stability, dose-rate dependence, linearity, detector shadowing, energy response, cross-calibration, angular dependence and positional sensitivity in SBRT and SRS. RESULTS: Large variation in the cross calibration factors was found between the seven individual detectors. For each detector, the energy dependence in the cross calibration factor was on average <0.6% across the beam qualities investigated (Co-60 Gamma Knife, and MV beams with TPR(20,10) 0.684–0.733). The angular corrections for individual fields were up to 5%, and varied with field size. However, the average angular dependence for all fields in a typical SRS treatment delivery was <1%. The overall measurement uncertainty was 3.6% and 3.1% (2σ) for an SRS and SBRT treatment plan respectively. CONCLUSION: Synthetic diamond detectors were found to be reliable and robust for end-to-end dosimetry in SBRT and SRS applications. Orientation of the detector relative to the beam axis is an important consideration, as significant corrections are required for angular dependence.
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spelling pubmed-85367792021-10-29 Characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery Shaw, Maddison Lye, Jessica Alves, Andrew Keehan, Stephanie Lehmann, Joerg Hanlon, Maximilian Kenny, John Baines, John Porumb, Claudiu Geso, Moshi Brown, Rhonda Phys Imaging Radiat Oncol Original Research Article BACKGROUND AND PURPOSE: Synthetic diamond detectors offer real time measurement of dose in radiotherapy applications which require high spatial resolution. Additional considerations and corrections are required for measurements where the diamond detector is orientated at various angles to the incident beam. This study investigated diamond detectors for end-to-end testing of Stereotactic Body Radiotherapy (SBRT) and Stereotactic Radiosurgery (SRS) in the context of dosimetry audits. MATERIAL AND METHODS: Seven individual diamond detectors were investigated and compared with respect to warm up stability, dose-rate dependence, linearity, detector shadowing, energy response, cross-calibration, angular dependence and positional sensitivity in SBRT and SRS. RESULTS: Large variation in the cross calibration factors was found between the seven individual detectors. For each detector, the energy dependence in the cross calibration factor was on average <0.6% across the beam qualities investigated (Co-60 Gamma Knife, and MV beams with TPR(20,10) 0.684–0.733). The angular corrections for individual fields were up to 5%, and varied with field size. However, the average angular dependence for all fields in a typical SRS treatment delivery was <1%. The overall measurement uncertainty was 3.6% and 3.1% (2σ) for an SRS and SBRT treatment plan respectively. CONCLUSION: Synthetic diamond detectors were found to be reliable and robust for end-to-end dosimetry in SBRT and SRS applications. Orientation of the detector relative to the beam axis is an important consideration, as significant corrections are required for angular dependence. Elsevier 2021-10-19 /pmc/articles/PMC8536779/ /pubmed/34722939 http://dx.doi.org/10.1016/j.phro.2021.10.002 Text en Crown Copyright © 2021 Published by Elsevier B.V. on behalf of European Society of Radiotherapy & Oncology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research Article
Shaw, Maddison
Lye, Jessica
Alves, Andrew
Keehan, Stephanie
Lehmann, Joerg
Hanlon, Maximilian
Kenny, John
Baines, John
Porumb, Claudiu
Geso, Moshi
Brown, Rhonda
Characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery
title Characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery
title_full Characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery
title_fullStr Characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery
title_full_unstemmed Characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery
title_short Characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery
title_sort characterisation of a synthetic diamond detector for end-to-end dosimetry in stereotactic body radiotherapy and radiosurgery
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536779/
https://www.ncbi.nlm.nih.gov/pubmed/34722939
http://dx.doi.org/10.1016/j.phro.2021.10.002
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