ASP-Enzymosomes with Saccharomyces cerevisiae Asparaginase II Expressed in Pichia pastoris: Formulation Design and In Vitro Studies of a Potential Antileukemic Drug

The bacterial enzyme asparaginase is the main treatment option for acute lymphoblastic leukemia. However, it causes side effects, such as immunological reactions, and presents undesirable glutaminase activity. As an alternative, we have been studying asparaginase II from Saccharomyces cerevisiae, co...

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Detalles Bibliográficos
Autores principales: Girão, Luciana F. C., Carvalheiro, Manuela Colla, Ferreira-Silva, Margarida, da Rocha, Surza L. G., Perales, Jonas, Martins, M. Bárbara F., Ferrara, Maria Antonieta, Bon, Elba P. S., Corvo, M. Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536964/
https://www.ncbi.nlm.nih.gov/pubmed/34681778
http://dx.doi.org/10.3390/ijms222011120

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