New Drugs Bringing New Challenges to AML: A Brief Review

The better understanding of the genomic landscape in acute myeloid leukaemia (AML) has progressively paved the way for precision medicine in AML. There is a growing number of drugs with novel mechanisms of action and unique side-effect profiles. This review examines the impact of evolving novel ther...

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Detalles Bibliográficos
Autores principales: Yeoh, Zhi Han, Bajel, Ashish, Wei, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537004/
https://www.ncbi.nlm.nih.gov/pubmed/34683144
http://dx.doi.org/10.3390/jpm11101003
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author Yeoh, Zhi Han
Bajel, Ashish
Wei, Andrew H.
author_facet Yeoh, Zhi Han
Bajel, Ashish
Wei, Andrew H.
author_sort Yeoh, Zhi Han
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description The better understanding of the genomic landscape in acute myeloid leukaemia (AML) has progressively paved the way for precision medicine in AML. There is a growing number of drugs with novel mechanisms of action and unique side-effect profiles. This review examines the impact of evolving novel therapies on survival in AML and the challenges that ensue.
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spelling pubmed-85370042021-10-24 New Drugs Bringing New Challenges to AML: A Brief Review Yeoh, Zhi Han Bajel, Ashish Wei, Andrew H. J Pers Med Review The better understanding of the genomic landscape in acute myeloid leukaemia (AML) has progressively paved the way for precision medicine in AML. There is a growing number of drugs with novel mechanisms of action and unique side-effect profiles. This review examines the impact of evolving novel therapies on survival in AML and the challenges that ensue. MDPI 2021-10-03 /pmc/articles/PMC8537004/ /pubmed/34683144 http://dx.doi.org/10.3390/jpm11101003 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yeoh, Zhi Han
Bajel, Ashish
Wei, Andrew H.
New Drugs Bringing New Challenges to AML: A Brief Review
title New Drugs Bringing New Challenges to AML: A Brief Review
title_full New Drugs Bringing New Challenges to AML: A Brief Review
title_fullStr New Drugs Bringing New Challenges to AML: A Brief Review
title_full_unstemmed New Drugs Bringing New Challenges to AML: A Brief Review
title_short New Drugs Bringing New Challenges to AML: A Brief Review
title_sort new drugs bringing new challenges to aml: a brief review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537004/
https://www.ncbi.nlm.nih.gov/pubmed/34683144
http://dx.doi.org/10.3390/jpm11101003
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