Cargando…

The Structure, Activity, and Function of the SETD3 Protein Histidine Methyltransferase

SETD3 has been recently identified as a long sought, actin specific histidine methyltransferase that catalyzes the Nτ-methylation reaction of histidine 73 (H73) residue in human actin or its equivalent in other metazoans. Its homologs are widespread among multicellular eukaryotes and expressed in mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Witecka, Apolonia, Kwiatkowski, Sebastian, Ishikawa, Takao, Drozak, Jakub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537074/ https://www.ncbi.nlm.nih.gov/pubmed/34685411 http://dx.doi.org/10.3390/life11101040

Ejemplares similares

Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin
por: Hintzen, Jordi C. J., et al.
Publicado: (2022)

SETD3 protein is the actin-specific histidine N-methyltransferase
por: Kwiatkowski, Sebastian, et al.
Publicado: (2018)

Structural insights into SETD3-mediated histidine methylation on β-actin
por: Guo, Qiong, et al.
Publicado: (2019)

Structural basis for the target specificity of actin histidine methyltransferase SETD3
por: Dai, Shaobo, et al.
Publicado: (2019)

SETD3 is an Actin Histidine Methyltransferase that Prevents Primary Dystocia
por: Wilkinson, Alex W., et al.
Publicado: (2019)

Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104)
por: Kwiatkowski, Sebastian, et al.
Publicado: (2022)

Structure, activity and function of the lysine methyltransferase SETD5
por: Li, Mingyang, et al.
Publicado: (2023)

The dynamic conformational landscape of the protein methyltransferase SETD8
por: Chen, Shi, et al.
Publicado: (2019)

Roles for the methyltransferase SETD8 in DNA damage repair
por: Xu, Libo, et al.
Publicado: (2022)

Enterovirus Pathogenesis Requires the Host Methyltransferase SETD3
por: Diep, Jonathan, et al.
Publicado: (2019)

Peptide inhibition of the SETD6 methyltransferase catalytic activity
por: Feldman, Michal, et al.
Publicado: (2017)

The emerging role of lysine methyltransferase SETD8 in human diseases
por: Milite, Ciro, et al.
Publicado: (2016)

Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate
por: Schuhmacher, Maren Kirstin, et al.
Publicado: (2020)

Insights into the stereoselectivity of human SETD7 methyltransferase
por: Tang, Bowen, et al.
Publicado: (2019)

Molecular Identification of Carnosine N-Methyltransferase as Chicken Histamine N-Methyltransferase-Like Protein (HNMT-Like)
por: Drozak, Jakub, et al.
Publicado: (2013)

Molecular basis for histidine N3-specific methylation of actin H73 by SETD3
por: Zheng, Yihui, et al.
Publicado: (2020)

The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase
por: Seervai, Riyad N. H., et al.
Publicado: (2020)

Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase
por: Yang, Shuang, et al.
Publicado: (2016)

Author Correction: Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate
por: Schuhmacher, Maren Kirstin, et al.
Publicado: (2020)

Biological processes and signal transduction pathways regulated by the protein methyltransferase SETD7 and their significance in cancer
por: Batista, Inês de Albuquerque Almeida, et al.
Publicado: (2018)

Histone methyltransferase SETD2: a potential tumor suppressor in solid cancers
por: Chen, Rui, et al.
Publicado: (2020)

Methyltransferase SETD2 mediates hepatoprotection of berberine against steatosis
por: Dai, Li, et al.
Publicado: (2022)

The histone methyltransferase SETD2 negatively regulates cell size
por: Molenaar, Thom M., et al.
Publicado: (2022)

Structure, Activity and Function of the NSD3 Protein Lysine Methyltransferase
por: Rathert, Philipp
Publicado: (2021)

SETD3 Methyltransferase Regulates PLK1 Expression to Promote In Situ Hepatic Carcinogenesis
por: Cheng, Meng, et al.
Publicado: (2022)

A Systematic Review to Define the Multi-Faceted Role of Lysine Methyltransferase SETD7 in Cancer
por: Monteiro, Fátima Liliana, et al.
Publicado: (2022)

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
por: Parker, H, et al.
Publicado: (2016)

The histone methyltransferase Setd2 is indispensable for V(D)J recombination
por: Ji, Zhongzhong, et al.
Publicado: (2019)

PAK4 methylation by the methyltransferase SETD6 attenuates cell adhesion
por: Vershinin, Zlata, et al.
Publicado: (2020)

Histone methyltransferase SETD1A participates in lung cancer progression
por: Du, Mei, et al.
Publicado: (2021)

Histone Methyltransferase SETD2 Is Required for Porcine Early Embryonic Development
por: Shao, Weini, et al.
Publicado: (2022)

Inhibition of histone methyltransferase SETD8 represses DNA virus replication
por: Chen, Lin, et al.
Publicado: (2022)

Structure, Activity and Function of the Protein Arginine Methyltransferase 6
por: Gupta, Somlee, et al.
Publicado: (2021)

Structure, Activity and Function of the SETDB1 Protein Methyltransferase
por: Markouli, Mariam, et al.
Publicado: (2021)

Structure, Activity, and Function of SETMAR Protein Lysine Methyltransferase
por: Tellier, Michael
Publicado: (2021)

Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8
por: Ma, Anqi, et al.
Publicado: (2014)

Lysine methyltransferase SETD6 modifies histones on a glycine-lysine motif
por: Binda, Olivier
Publicado: (2019)

The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis
por: Liu, Min, et al.
Publicado: (2021)

Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer
por: Ishii, Takeshi, et al.
Publicado: (2022)

The disordered regions of the methyltransferase SETD2 govern its function by regulating its proteolysis and phase separation
por: Bhattacharya, Saikat, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jr8lciqah5jshp5nev9ouullqi