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COVID-19 Infection and Neuropathological Features
The pathology associated with COVID-19 infection is progressively being revealed. Recent postmortem assessments have revealed acute airway inflammation as well as diffuse alveolar damage, which bears resemblance to severe acute respiratory syndromes induced by both SARS-CoV and MERS-CoV infections....
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537119/ https://www.ncbi.nlm.nih.gov/pubmed/34677488 http://dx.doi.org/10.3390/medicines8100059 |
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| author | Freire-de-Lima, Leonardo Scovino, Aline Miranda Marques da Fonseca, Leonardo Barreto Menezes, Camilla Cristie Santos, Carlos Antonio do Nascimento Freire de Lima, Marco Edilson Decote-Ricardo, Debora Freire-de-Lima, Matheus da Costa, Kelli Monteiro dos Reis, Jhenifer Santos Rodrigues da Costa Santos, Marcos André Freire-de-Lima, Celio Geraldo Morrot, Alexandre |
| author_facet | Freire-de-Lima, Leonardo Scovino, Aline Miranda Marques da Fonseca, Leonardo Barreto Menezes, Camilla Cristie Santos, Carlos Antonio do Nascimento Freire de Lima, Marco Edilson Decote-Ricardo, Debora Freire-de-Lima, Matheus da Costa, Kelli Monteiro dos Reis, Jhenifer Santos Rodrigues da Costa Santos, Marcos André Freire-de-Lima, Celio Geraldo Morrot, Alexandre |
| author_sort | Freire-de-Lima, Leonardo |
| collection | PubMed |
| description | The pathology associated with COVID-19 infection is progressively being revealed. Recent postmortem assessments have revealed acute airway inflammation as well as diffuse alveolar damage, which bears resemblance to severe acute respiratory syndromes induced by both SARS-CoV and MERS-CoV infections. Although recent papers have highlighted some neuropathologies associated with COVID-19 infection, little is known about this topic of great importance in the area of public health. Here, we discuss how neuroinflammation related to COVID-19 could be triggered by direct viral neuroinvasion and/or cytokine release over the course of the infection. |
| format | Online Article Text |
| id | pubmed-8537119 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-85371192021-10-24 COVID-19 Infection and Neuropathological Features Freire-de-Lima, Leonardo Scovino, Aline Miranda Marques da Fonseca, Leonardo Barreto Menezes, Camilla Cristie Santos, Carlos Antonio do Nascimento Freire de Lima, Marco Edilson Decote-Ricardo, Debora Freire-de-Lima, Matheus da Costa, Kelli Monteiro dos Reis, Jhenifer Santos Rodrigues da Costa Santos, Marcos André Freire-de-Lima, Celio Geraldo Morrot, Alexandre Medicines (Basel) Opinion The pathology associated with COVID-19 infection is progressively being revealed. Recent postmortem assessments have revealed acute airway inflammation as well as diffuse alveolar damage, which bears resemblance to severe acute respiratory syndromes induced by both SARS-CoV and MERS-CoV infections. Although recent papers have highlighted some neuropathologies associated with COVID-19 infection, little is known about this topic of great importance in the area of public health. Here, we discuss how neuroinflammation related to COVID-19 could be triggered by direct viral neuroinvasion and/or cytokine release over the course of the infection. MDPI 2021-10-11 /pmc/articles/PMC8537119/ /pubmed/34677488 http://dx.doi.org/10.3390/medicines8100059 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Opinion Freire-de-Lima, Leonardo Scovino, Aline Miranda Marques da Fonseca, Leonardo Barreto Menezes, Camilla Cristie Santos, Carlos Antonio do Nascimento Freire de Lima, Marco Edilson Decote-Ricardo, Debora Freire-de-Lima, Matheus da Costa, Kelli Monteiro dos Reis, Jhenifer Santos Rodrigues da Costa Santos, Marcos André Freire-de-Lima, Celio Geraldo Morrot, Alexandre COVID-19 Infection and Neuropathological Features |
| title | COVID-19 Infection and Neuropathological Features |
| title_full | COVID-19 Infection and Neuropathological Features |
| title_fullStr | COVID-19 Infection and Neuropathological Features |
| title_full_unstemmed | COVID-19 Infection and Neuropathological Features |
| title_short | COVID-19 Infection and Neuropathological Features |
| title_sort | covid-19 infection and neuropathological features |
| topic | Opinion |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537119/ https://www.ncbi.nlm.nih.gov/pubmed/34677488 http://dx.doi.org/10.3390/medicines8100059 |
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