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A Rabbit Model for the Evaluation of Drugs for Treating the Chronic Phase of Botulism

Antitoxin, the only licensed drug therapy for botulism, neutralizes circulating botulinum neurotoxin (BoNT). However, antitoxin is no longer effective when a critical amount of BoNT has already entered its target nerve cells. The outcome is a chronic phase of botulism that is characterized by prolon...

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Detalles Bibliográficos
Autores principales: Torgeman, Amram, Diamant, Eran, Dor, Eyal, Schwartz, Arieh, Baruchi, Tzadok, Ben David, Alon, Zichel, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537128/
https://www.ncbi.nlm.nih.gov/pubmed/34678971
http://dx.doi.org/10.3390/toxins13100679