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Cathepsin Release from Lysosomes Promotes Endocytosis of Clostridium perfringens Iota-Toxin

Iota-toxin from Clostridium perfringens type E is a binary toxin composed of two independent proteins: actin-ADP-ribosylating enzyme component, iota-a (Ia), and binding component, iota-b (Ib). Ib binds to target cell receptors and mediates the internalization of Ia into the cytoplasm. Extracellular...

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Detalles Bibliográficos
Autores principales:	Nagahama, Masahiro, Kobayashi, Keiko, Takehara, Masaya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537257/ https://www.ncbi.nlm.nih.gov/pubmed/34679014 http://dx.doi.org/10.3390/toxins13100721

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