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Electrospun Medicated Nanofibers for Wound Healing: Review

With the increasing demand for wound care and treatment worldwide, traditional dressings have been unable to meet the needs of the existing market due to their limited antibacterial properties and other defects. Electrospinning technology has attracted more and more researchers’ attention as a simpl...

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Detalles Bibliográficos
Autores principales: Liu, Xinkuan, Xu, Haixia, Zhang, Mingxin, Yu, Deng-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537333/
https://www.ncbi.nlm.nih.gov/pubmed/34677536
http://dx.doi.org/10.3390/membranes11100770
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author Liu, Xinkuan
Xu, Haixia
Zhang, Mingxin
Yu, Deng-Guang
author_facet Liu, Xinkuan
Xu, Haixia
Zhang, Mingxin
Yu, Deng-Guang
author_sort Liu, Xinkuan
collection PubMed
description With the increasing demand for wound care and treatment worldwide, traditional dressings have been unable to meet the needs of the existing market due to their limited antibacterial properties and other defects. Electrospinning technology has attracted more and more researchers’ attention as a simple and versatile manufacturing method. The electrospun nanofiber membrane has a unique structure and biological function similar to the extracellular matrix (ECM), and is considered an advanced wound dressing. They have significant potential in encapsulating and delivering active substances that promote wound healing. This article first discusses the common types of wound dressing, and then summarizes the development of electrospun fiber preparation technology. Finally, the polymers and common biologically active substances used in electrospinning wound dressings are summarized, and portable electrospinning equipment is also discussed. Additionally, future research needs are put forward.
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spelling pubmed-85373332021-10-24 Electrospun Medicated Nanofibers for Wound Healing: Review Liu, Xinkuan Xu, Haixia Zhang, Mingxin Yu, Deng-Guang Membranes (Basel) Review With the increasing demand for wound care and treatment worldwide, traditional dressings have been unable to meet the needs of the existing market due to their limited antibacterial properties and other defects. Electrospinning technology has attracted more and more researchers’ attention as a simple and versatile manufacturing method. The electrospun nanofiber membrane has a unique structure and biological function similar to the extracellular matrix (ECM), and is considered an advanced wound dressing. They have significant potential in encapsulating and delivering active substances that promote wound healing. This article first discusses the common types of wound dressing, and then summarizes the development of electrospun fiber preparation technology. Finally, the polymers and common biologically active substances used in electrospinning wound dressings are summarized, and portable electrospinning equipment is also discussed. Additionally, future research needs are put forward. MDPI 2021-10-09 /pmc/articles/PMC8537333/ /pubmed/34677536 http://dx.doi.org/10.3390/membranes11100770 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Liu, Xinkuan
Xu, Haixia
Zhang, Mingxin
Yu, Deng-Guang
Electrospun Medicated Nanofibers for Wound Healing: Review
title Electrospun Medicated Nanofibers for Wound Healing: Review
title_full Electrospun Medicated Nanofibers for Wound Healing: Review
title_fullStr Electrospun Medicated Nanofibers for Wound Healing: Review
title_full_unstemmed Electrospun Medicated Nanofibers for Wound Healing: Review
title_short Electrospun Medicated Nanofibers for Wound Healing: Review
title_sort electrospun medicated nanofibers for wound healing: review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537333/
https://www.ncbi.nlm.nih.gov/pubmed/34677536
http://dx.doi.org/10.3390/membranes11100770
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