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Host EPAC1 Modulates Rickettsial Adhesion to Vascular Endothelial Cells via Regulation of ANXA2 Y23 Phosphorylation

Introduction: Intracellular cAMP receptor exchange proteins directly activated by cAMP 1 (EPAC1) regulate obligate intracellular parasitic bacterium rickettsial adherence to and invasion into vascular endothelial cells (ECs). However, underlying precise mechanism(s) remain unclear. The aim of the st...

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Detalles Bibliográficos
Autores principales: Su, Zhengchen, Shelite, Thomas R., Qiu, Yuan, Chang, Qing, Wakamiya, Maki, Bei, Jiani, He, Xi, Zhou, Changcheng, Liu, Yakun, Nyong, Emmanuel, Liang, Yuejin, Gaitas, Angelo, Saito, Tais B., Gong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537355/
https://www.ncbi.nlm.nih.gov/pubmed/34684255
http://dx.doi.org/10.3390/pathogens10101307