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The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A

The paradigm of ligand-receptor interactions postulated as “one compound—one target” has been evolving; a multi-target, pleiotropic approach is now considered to be realistic. Novel series of 1,4,5,6,7,8-hexahydro-5-oxoquinolines, pyranopyrimidines and S-alkyl derivatives of pyranopyrimidines have b...

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Detalles Bibliográficos
Autores principales: Bisenieks, Egils, Vigante, Brigita, Petrovska, Ramona, Turovska, Baiba, Muhamadejev, Ruslan, Soloduns, Vitalijs, Velena, Astrida, Pajuste, Karlis, Saso, Luciano, Klovins, Janis, Duburs, Gunars, Mandrika, Ilona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537386/
https://www.ncbi.nlm.nih.gov/pubmed/34681211
http://dx.doi.org/10.3390/ph14100987