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The Shiga Toxin Receptor Globotriaosylceramide as Therapeutic Target in Shiga Toxin E. coli Mediated HUS

In 90% of the cases, childhood hemolytic uremic syndrome (HUS) is caused by an infection with the Shiga toxin (Stx) producing E. coli bacteria (STEC-HUS). Stx preferentially binds to its receptor, the glycosphingolipid, globotriaosylceramide (Gb3), present on the surface of human kidney cells and va...

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Detalles Bibliográficos
Autores principales:	Feitz, Wouter J. C., Bouwmeester, Romy, van der Velden, Thea J. A. M., Goorden, Susan, Licht, Christoph, van den Heuvel, Lambert P. J. W., van de Kar, Nicole C. A. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537462/ https://www.ncbi.nlm.nih.gov/pubmed/34683478 http://dx.doi.org/10.3390/microorganisms9102157

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