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Deprotometalation-Iodolysis and Direct Iodination of 1-Arylated 7-Azaindoles: Reactivity Studies and Molecule Properties

Five protocols were first compared for the copper-catalyzed C-N bond formation between 7-azaindole and aryl/heteroaryl iodides/bromides. The 1-arylated 7-azaindoles thus obtained were subjected to deprotometalation-iodolysis sequences using lithium 2,2,6,6-tetramethylpiperidide as the base and the c...

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Detalles Bibliográficos
Autores principales: Ameur Messaoud, Mohamed Yacine, Bentabed-Ababsa, Ghenia, Fajloun, Ziad, Hamze, Monzer, Halauko, Yury S., Ivashkevich, Oleg A., Matulis, Vadim E., Roisnel, Thierry, Dorcet, Vincent, Mongin, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537530/
https://www.ncbi.nlm.nih.gov/pubmed/34684895
http://dx.doi.org/10.3390/molecules26206314

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