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ATP1A1 Mutant in Aldosterone-Producing Adenoma Leads to Cell Proliferation

The molecular mechanisms by which ATP1A1 mutation-mediated cell proliferation or tumorigenesis in aldosterone-producing adenomas (APAs) have not been elucidated. First, we investigated whether the APA-associated ATP1A1 L104R mutation stimulated cell proliferation. Second, we aimed to clarify the mol...

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Detalles Bibliográficos
Autores principales: Kobuke, Kazuhiro, Oki, Kenji, Gomez-Sanchez, Celso E., Gomez-Sanchez, Elise P., Itcho, Kiyotaka, Ohno, Haruya, Nagano, Gaku, Yoshii, Yoko, Baba, Ryuta, Kodama, Takaya, Arihiro, Koji, Hattori, Noboru, Yoneda, Masayasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537586/
https://www.ncbi.nlm.nih.gov/pubmed/34681640
http://dx.doi.org/10.3390/ijms222010981