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Genomic Signatures in HPV-Associated Tumors

Papillomaviruses dysregulate the G1/S cell cycle transition in order to promote DNA synthesis in S phase, which is a requirement for viral replication. The human papillomaviruses (HPV) E6 and E7 oncoproteins mediate degradation of the cell cycle regulators p53 and Rb, which are two of the most unive...

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Detalles Bibliográficos
Autores principales:	Hussain, Suleman S., Lundine, Devon, Leeman, Jonathan E., Higginson, Daniel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537705/ https://www.ncbi.nlm.nih.gov/pubmed/34696429 http://dx.doi.org/10.3390/v13101998

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