The Expression Level of HIV-1 Vif Is Optimized by Nucleotide Changes in the Genomic SA1D2prox Region during the Viral Adaptation Process

HIV-1 Vif plays an essential role in viral replication by antagonizing anti-viral cellular restriction factors, a family of APOBEC3 proteins. We have previously shown that naturally-occurring single-nucleotide mutations in the SA1D2prox region, which surrounds the splicing acceptor 1 and splicing do...

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Detalles Bibliográficos
Autores principales: Koma, Takaaki, Doi, Naoya, Takemoto, Mai, Watanabe, Kyosuke, Yamamoto, Hideki, Nakashima, Satoshi, Adachi, Akio, Nomaguchi, Masako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537775/
https://www.ncbi.nlm.nih.gov/pubmed/34696508
http://dx.doi.org/10.3390/v13102079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537775/
https://www.ncbi.nlm.nih.gov/pubmed/34696508
http://dx.doi.org/10.3390/v13102079

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