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Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics

A proportion of patients with COVID-19 have symptoms past the acute disease phase, which may affect quality of life. It is important for clinicians to be aware of this “long-COVID-19” syndrome to better diagnose, treat, and prevent it. We reviewed clinical and laboratory characteristics of a COVID-1...

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Autores principales: Kozak, Robert, Armstrong, Susan M., Salvant, Elsa, Ritzker, Claudia, Feld, Jordan, Biondi, Mia J., Tsui, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537802/
https://www.ncbi.nlm.nih.gov/pubmed/34684195
http://dx.doi.org/10.3390/pathogens10101246
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author Kozak, Robert
Armstrong, Susan M.
Salvant, Elsa
Ritzker, Claudia
Feld, Jordan
Biondi, Mia J.
Tsui, Hubert
author_facet Kozak, Robert
Armstrong, Susan M.
Salvant, Elsa
Ritzker, Claudia
Feld, Jordan
Biondi, Mia J.
Tsui, Hubert
author_sort Kozak, Robert
collection PubMed
description A proportion of patients with COVID-19 have symptoms past the acute disease phase, which may affect quality of life. It is important for clinicians to be aware of this “long-COVID-19” syndrome to better diagnose, treat, and prevent it. We reviewed clinical and laboratory characteristics of a COVID-19 cohort in a Toronto, Ontario tertiary care center. Demographic, clinical, and laboratory data were collected, and patients were classified as “long-COVID-19” or “non-long-COVID-19” using consensus criteria. Of 397 patients who tested positive for COVID-19, 223 met inclusion criteria, and 62 (27%) had long-COVID-19. These patients had a similar age distribution compared to non-long-COVID-19 patients overall but were younger in the admitted long COVID-19 group. The long-COVID-19 group had more inpatients compared to the non-long-COVID-19 group (39% vs. 25%) and more frequent supplemental oxygen or mechanical ventilation use. However, long-COVID-19 patients did not differ by duration of mechanical ventilation, length of stay, comorbidities, or values of common laboratory tests ordered. The most frequent symptoms associated with long-COVID-19 were fatigue and weakness, as reported most commonly by the infectious disease, respirology and cardiology disciplines. In conclusion, by retrospective chart review, 27% of COVID-19 patients presenting to a tertiary care center in Toronto, Canada, were found to meet criteria for long-COVID-19. Past medical history and routine laboratory testing at presentation did not predict for long-COVID-19 development.
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spelling pubmed-85378022021-10-24 Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics Kozak, Robert Armstrong, Susan M. Salvant, Elsa Ritzker, Claudia Feld, Jordan Biondi, Mia J. Tsui, Hubert Pathogens Article A proportion of patients with COVID-19 have symptoms past the acute disease phase, which may affect quality of life. It is important for clinicians to be aware of this “long-COVID-19” syndrome to better diagnose, treat, and prevent it. We reviewed clinical and laboratory characteristics of a COVID-19 cohort in a Toronto, Ontario tertiary care center. Demographic, clinical, and laboratory data were collected, and patients were classified as “long-COVID-19” or “non-long-COVID-19” using consensus criteria. Of 397 patients who tested positive for COVID-19, 223 met inclusion criteria, and 62 (27%) had long-COVID-19. These patients had a similar age distribution compared to non-long-COVID-19 patients overall but were younger in the admitted long COVID-19 group. The long-COVID-19 group had more inpatients compared to the non-long-COVID-19 group (39% vs. 25%) and more frequent supplemental oxygen or mechanical ventilation use. However, long-COVID-19 patients did not differ by duration of mechanical ventilation, length of stay, comorbidities, or values of common laboratory tests ordered. The most frequent symptoms associated with long-COVID-19 were fatigue and weakness, as reported most commonly by the infectious disease, respirology and cardiology disciplines. In conclusion, by retrospective chart review, 27% of COVID-19 patients presenting to a tertiary care center in Toronto, Canada, were found to meet criteria for long-COVID-19. Past medical history and routine laboratory testing at presentation did not predict for long-COVID-19 development. MDPI 2021-09-26 /pmc/articles/PMC8537802/ /pubmed/34684195 http://dx.doi.org/10.3390/pathogens10101246 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kozak, Robert
Armstrong, Susan M.
Salvant, Elsa
Ritzker, Claudia
Feld, Jordan
Biondi, Mia J.
Tsui, Hubert
Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics
title Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics
title_full Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics
title_fullStr Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics
title_full_unstemmed Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics
title_short Recognition of Long-COVID-19 Patients in a Canadian Tertiary Hospital Setting: A Retrospective Analysis of Their Clinical and Laboratory Characteristics
title_sort recognition of long-covid-19 patients in a canadian tertiary hospital setting: a retrospective analysis of their clinical and laboratory characteristics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537802/
https://www.ncbi.nlm.nih.gov/pubmed/34684195
http://dx.doi.org/10.3390/pathogens10101246
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