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Progesterone Metabolism by Human and Rat Hepatic and Intestinal Tissue
Following oral administration, the bioavailability of progesterone is low and highly variable. As a result, no clinically relevant, natural progesterone oral formulation is available. After oral delivery, first-pass metabolism initially occurs in the intestines; however, very little information on p...
Autores principales: | Coombes, Zoe, Plant, Katie, Freire, Cristina, Basit, Abdul W., Butler, Philip, Conlan, R. Steven, Gonzalez, Deyarina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537901/ https://www.ncbi.nlm.nih.gov/pubmed/34684000 http://dx.doi.org/10.3390/pharmaceutics13101707 |
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