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School-Level Variation in Coverage of Co-Administered dTpa and HPV Dose 1 in Three Australian States
Background: Australian adolescents are routinely offered HPV and dTpa (diphtheria, tetanus, pertussis) vaccines simultaneously in the secondary school vaccination program. We identified schools where HPV initiation was lower than dTpa coverage and associated school-level factors across three states....
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537995/ https://www.ncbi.nlm.nih.gov/pubmed/34696310 http://dx.doi.org/10.3390/vaccines9101202 |
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author | Vujovich-Dunn, Cassandra Skinner, Susan Rachel Brotherton, Julia Wand, Handan Sisnowski, Jana Lorch, Rebecca Veitch, Mark Sheppeard, Vicky Effler, Paul Gidding, Heather Venn, Alison Davies, Cristyn Hocking, Jane Whop, Lisa J. Leask, Julie Canfell, Karen Sanci, Lena Smith, Megan Kang, Melissa Temple-Smith, Meredith Kidd, Michael Burns, Sharyn Selvey, Linda Meijer, Dennis Ennis, Sonya Thomson, Chloe A. Lane, Nikole Kaldor, John Guy, Rebecca |
author_facet | Vujovich-Dunn, Cassandra Skinner, Susan Rachel Brotherton, Julia Wand, Handan Sisnowski, Jana Lorch, Rebecca Veitch, Mark Sheppeard, Vicky Effler, Paul Gidding, Heather Venn, Alison Davies, Cristyn Hocking, Jane Whop, Lisa J. Leask, Julie Canfell, Karen Sanci, Lena Smith, Megan Kang, Melissa Temple-Smith, Meredith Kidd, Michael Burns, Sharyn Selvey, Linda Meijer, Dennis Ennis, Sonya Thomson, Chloe A. Lane, Nikole Kaldor, John Guy, Rebecca |
author_sort | Vujovich-Dunn, Cassandra |
collection | PubMed |
description | Background: Australian adolescents are routinely offered HPV and dTpa (diphtheria, tetanus, pertussis) vaccines simultaneously in the secondary school vaccination program. We identified schools where HPV initiation was lower than dTpa coverage and associated school-level factors across three states. Methods: HPV vaccination initiation rates and dTpa vaccination coverage in 2016 were calculated using vaccine databases and school enrolment data. A multivariate analysis assessed sociodemographic and school-level factors associated with HPV initiation being >5% absolute lower than dTpa coverage. Results: Of 1280 schools included, the median school-level HPV initiation rate was 85% (interquartile range (IQR):75–90%) and the median dTpa coverage was 86% (IQR:75–92%). Nearly a quarter (24%) of all schools had HPV vaccination initiation >5% lower than dTpa coverage and 11 % had >10% difference. School-level factors independently associated with >5% difference were remote schools (aOR:3.5, 95% CI = 1.7–7.2) and schools in major cities (aOR:1.8, 95% CI = 1.0–3.0), small schools (aOR:3.3, 95% CI = 2.3–5.7), higher socioeconomic advantage (aOR:1.7, 95% CI = 1.1–2.6), and lower proportions of Language-background-other-than-English (aOR:1.9, 95% CI = 1.2–3.0). Conclusion: The results identified a quarter of schools had lower HPV than dTpa initiation coverage, which may indicate HPV vaccine hesitancy, and the difference was more likely in socioeconomically advantaged schools. As hesitancy is context specific, it is important to understand the potential drivers of hesitancy and future research needs to understand the reasons driving differential uptake. |
format | Online Article Text |
id | pubmed-8537995 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85379952021-10-24 School-Level Variation in Coverage of Co-Administered dTpa and HPV Dose 1 in Three Australian States Vujovich-Dunn, Cassandra Skinner, Susan Rachel Brotherton, Julia Wand, Handan Sisnowski, Jana Lorch, Rebecca Veitch, Mark Sheppeard, Vicky Effler, Paul Gidding, Heather Venn, Alison Davies, Cristyn Hocking, Jane Whop, Lisa J. Leask, Julie Canfell, Karen Sanci, Lena Smith, Megan Kang, Melissa Temple-Smith, Meredith Kidd, Michael Burns, Sharyn Selvey, Linda Meijer, Dennis Ennis, Sonya Thomson, Chloe A. Lane, Nikole Kaldor, John Guy, Rebecca Vaccines (Basel) Article Background: Australian adolescents are routinely offered HPV and dTpa (diphtheria, tetanus, pertussis) vaccines simultaneously in the secondary school vaccination program. We identified schools where HPV initiation was lower than dTpa coverage and associated school-level factors across three states. Methods: HPV vaccination initiation rates and dTpa vaccination coverage in 2016 were calculated using vaccine databases and school enrolment data. A multivariate analysis assessed sociodemographic and school-level factors associated with HPV initiation being >5% absolute lower than dTpa coverage. Results: Of 1280 schools included, the median school-level HPV initiation rate was 85% (interquartile range (IQR):75–90%) and the median dTpa coverage was 86% (IQR:75–92%). Nearly a quarter (24%) of all schools had HPV vaccination initiation >5% lower than dTpa coverage and 11 % had >10% difference. School-level factors independently associated with >5% difference were remote schools (aOR:3.5, 95% CI = 1.7–7.2) and schools in major cities (aOR:1.8, 95% CI = 1.0–3.0), small schools (aOR:3.3, 95% CI = 2.3–5.7), higher socioeconomic advantage (aOR:1.7, 95% CI = 1.1–2.6), and lower proportions of Language-background-other-than-English (aOR:1.9, 95% CI = 1.2–3.0). Conclusion: The results identified a quarter of schools had lower HPV than dTpa initiation coverage, which may indicate HPV vaccine hesitancy, and the difference was more likely in socioeconomically advantaged schools. As hesitancy is context specific, it is important to understand the potential drivers of hesitancy and future research needs to understand the reasons driving differential uptake. MDPI 2021-10-19 /pmc/articles/PMC8537995/ /pubmed/34696310 http://dx.doi.org/10.3390/vaccines9101202 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Vujovich-Dunn, Cassandra Skinner, Susan Rachel Brotherton, Julia Wand, Handan Sisnowski, Jana Lorch, Rebecca Veitch, Mark Sheppeard, Vicky Effler, Paul Gidding, Heather Venn, Alison Davies, Cristyn Hocking, Jane Whop, Lisa J. Leask, Julie Canfell, Karen Sanci, Lena Smith, Megan Kang, Melissa Temple-Smith, Meredith Kidd, Michael Burns, Sharyn Selvey, Linda Meijer, Dennis Ennis, Sonya Thomson, Chloe A. Lane, Nikole Kaldor, John Guy, Rebecca School-Level Variation in Coverage of Co-Administered dTpa and HPV Dose 1 in Three Australian States |
title | School-Level Variation in Coverage of Co-Administered dTpa and HPV Dose 1 in Three Australian States |
title_full | School-Level Variation in Coverage of Co-Administered dTpa and HPV Dose 1 in Three Australian States |
title_fullStr | School-Level Variation in Coverage of Co-Administered dTpa and HPV Dose 1 in Three Australian States |
title_full_unstemmed | School-Level Variation in Coverage of Co-Administered dTpa and HPV Dose 1 in Three Australian States |
title_short | School-Level Variation in Coverage of Co-Administered dTpa and HPV Dose 1 in Three Australian States |
title_sort | school-level variation in coverage of co-administered dtpa and hpv dose 1 in three australian states |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537995/ https://www.ncbi.nlm.nih.gov/pubmed/34696310 http://dx.doi.org/10.3390/vaccines9101202 |
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