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Identification of a Novel Neuropeptide S Receptor Antagonist Scaffold Based on the SHA-68 Core

Activation of the neuropeptide S receptor (NPSR) system has been shown to produce anxiolytic-like actions, arousal, and enhance memory consolidation, whereas blockade of the NPSR has been shown to reduce relapse to substances of abuse and duration of anesthetics. We report here the discovery of a no...

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Detalles Bibliográficos
Autores principales: Zarkin, Allison, Jahan, Rajwana, Uprety, Rajendra, Zhang, Yanan, McElhinny, Charles, Snyder, Rodney, Gay, Elaine, Jewula, Gabriel, Bool, Heather, Clark, Stewart D, Runyon, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538004/
https://www.ncbi.nlm.nih.gov/pubmed/34681248
http://dx.doi.org/10.3390/ph14101024