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CHIR99021, trough GSK-3β Targeting, Reduces Epithelioid Sarcoma Cell Proliferation by Activating Mitotic Catastrophe and Autophagy
Epithelioid sarcoma (ES) is a rare disease representing <1% of soft tissue sarcomas. Current therapies are based on anthracycline alone or in combination with ifosfamide or other cytotoxic drugs. ES is still characterized by a poor prognosis with high rates of recurrence. Indeed, for years, ES su...
Autores principales: | Russi, Sabino, Sgambato, Alessandro, Bochicchio, Anna Maria, Zoppoli, Pietro, Aieta, Michele, Capobianco, Alba Maria Lucia, Ruggieri, Vitalba, Zifarone, Emanuela, Falco, Geppino, Laurino, Simona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538073/ https://www.ncbi.nlm.nih.gov/pubmed/34681807 http://dx.doi.org/10.3390/ijms222011147 |
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