Role of PI3K-AKT-mTOR Pathway as a Pro-Survival Signaling and Resistance-Mediating Mechanism to Therapy of Prostate Cancer

Androgen deprivation therapy (ADT) and androgen receptor (AR)-targeted therapy are the gold standard options for treating prostate cancer (PCa). These are initially effective, as localized and the early stage of metastatic disease are androgen- and castration-sensitive. The tumor strongly relies on...

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Detalles Bibliográficos
Autores principales: Pungsrinont, Thanakorn, Kallenbach, Julia, Baniahmad, Aria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538152/
https://www.ncbi.nlm.nih.gov/pubmed/34681745
http://dx.doi.org/10.3390/ijms222011088

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