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Preparation and In Vitro/In Vivo Evaluation of Orally Disintegrating/Modified-Release Praziquantel Tablets

This study was designed to develop orally disintegrating/sustained-release praziquantel (PZQ) tablets using the hot-melt extrusion (HME) technique and direct compression, and subsequently evaluate their release in in vitro and in vivo pharmacokinetics. For the extrusion process, hypromellose acetate...

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Detalles Bibliográficos
Autores principales:	Wen, Xuemei, Deng, Zhaoyou, Xu, Yangfeng, Yan, Guoqing, Deng, Xin, Wu, Liqin, Liang, Qiuling, Fang, Fang, Feng, Xin, Yu, Meiling, He, Jiakang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538324/ https://www.ncbi.nlm.nih.gov/pubmed/34683860 http://dx.doi.org/10.3390/pharmaceutics13101567

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